Bystander edits occurs during base editing when one or more bases
are altered in addition to the target base in the activity window.
Bystander activity poses a significant challenge in gene editing as
those undesired changes might result in different phenotype outcomes.
The bystander activity for certain guides and targets are listed
below. The table is dynamic and can be filter by clicking at guides or
targets or by using the search bar. Bar charts can be enlarged by clicking on them.
Legend:
Flanking section
Editing window (3-10)
gRNA / Sequence mismatch